MightlyFly, a US-based startup specializing in autonomous hybrid eVTOL cargo aircraft, has announced a $50 million, five-year contract with a leading California-based healthcare diagnostics provider to deliver same-day, expedited logistics of medical diagnostic test kits. The service will initially be launched in California, before being expanded to Nevada and scaling nationwide thereafter.
According to the company, “this partnership marks one of the largest commercial agreements to date to bring autonomous cargo eVTOL aircraft into healthcare logistics at scale.
MightyFly is a provider of expedited logistics services and a leading manufacturer and operator of autonomous, fixed-wing, hybrid eVTOL cargo aircraft with payload capacities of 100 pounds, a range of 1,000 miles, and a speed of 150 mph.
Based in the San Francisco Bay Area, MightyFly was founded in 2019 with backing from several major investment organizations. The company was named a “Top Supply Chain Startup to Watch” in 2022 by Business Insider. According to the company’s website, “MightyFly’s mission is to provide fast, affordable, and low-emissions expedited deliveries to businesses and governments.
MightyFly’s autonomous eVTOL service will provide same-day deliveries, with in-transit cold storage as an optional feature, directly from pharmacies, clinics, and retail stores to the healthcare provider’s labs.
This will reduce dependence on costly commercial airline shipments and inefficient ground transportation, according to the company. In addition to offering speed and reliability, MightyFly’s aircraft offer a sustainable alternative, cutting emissions by up to 64% compared to road-based vans and 92% compared to small aircraft, the company added.
This landmark agreement potentially signals a pivotal shift for the logistics industry. Unlike unmanned aerial vehicles (UAVs) that typically deliver a single item between two points, MightyFly’s aircraft can autonomously transport hundreds of test kits to and from multiple destinations on a single route.
The result, says the company, is three times faster deliveries enabled with eVTOL door-to-door shipments, faster turnaround times for diagnostic results, and 70% lower operating costs than legacy logistics services. By doing so, MightyFly aims to ultimately expand access to care for the provider’s customers and their end-users, including major retailers such as Amazon, Walmart, CVS, and Kroger, as well as clinics and educational institutions.
“Our mission is to provide efficient access to goods. In healthcare, that means enabling the most expeditious, accessible, and affordable care,” said Manal Habib, CEO of MightyFly. “With our Cento aircraft, we will deliver resilient, cost-efficient, and reliable expedited logistics at scale. With its 1,000-mile range and cargo capacities in the hundreds of items, our aircraft will transform expedited logistics and healthcare access. With its eVTOL, healthcare is no longer constrained by roads and runways; lifesaving supplies, and critical goods can now fly everywhere, directly and efficiently.”
By MightyFly’s calculations, the US pharmaceutical logistics market exceeds $100 billion annually, while healthcare logistics approaches $90 billion. Both are projected to more than double in the coming decade as diagnostics, personalized medicine, and resilient supply chains become critical to healthcare delivery.
The latest announcement comes as MightyFly has marked a series of milestones so far in 2025. So far, over 400 flights have been demonstrated, including automated cargo loading and unloading. The company has also carried out testing with the US Air Force to advance autonomous aerial logistics technology.
It says it has over $210 million in signed commercial Letters of Intent (LOIs), which “validates broad market demand,” and finally, in April 2025, the company received FAA authorization to test in five California airspaces, up to 5,000 ft, including seven airports and multiple flight corridors.
“With this latest contract and the momentum of our recent achievements, MightyFly is leading the next stage of autonomous aerial logistics, moving beyond small drones to transporting large volumes of goods at scale,” Habib added. “This is just the beginning, and healthcare is the first step. Our hybrid eVTOL platform will redefine expedited logistics across retail, defense, manufacturing, and commercial supply chains worldwide.”
